About the database

Campylobacter is the genus of Gram-negative, non-spore forming rods, spiral shaped bacteria. It is responsible to cause infectious diseases, campylobacteriosis in human body. Campylobacter jejuni RM1221 (CjR) is the species that induce acute gastroenteritis and bacterial food poisoning in human body. Normal infection of CjR causes uncomplicated gastroenteritis but severe infection may result abdominal cramps, fever or even serious diseases like diarrhea, GuillainBarré Syndrome or Miller Fischer Syndrome. CjR transmits to human by various sources associated with lack of awareness like undercooked livestock meat, poultry, unpasteurized milk or contaminated sources such as water. Antibiotic treatment against CjR becoming in sufficient due to multiple antibiotic resistance. This resistance requires special attention as CjR is capable to transmit the resistant genes to other strains. In 2000, primary genome sequence of CjR was invented but detailed information including variations and polymorphisms in complete genome sequences of different strains was published in 2006.

We have created an open access database named CampyNIBase to store all identified and characterized therapeutic targets for the improvement of medication system against CjR. In order to enrich the database other relevant campylobacter information such as built 3D model, expressed sequence tags (EST) sequences, potential epitopes and experimental drugs are incorporated in CampyNIBase through extensive literature survey.

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